Faculty of Health, Medicine and Life Sciences

Module Information
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MBS1401  - Science and Technology of Regenerative Therapeutics

Period 3: from 8-1-2024 to 9-3-2024
Co-requisites:
None
Coordinator: Tienen, F. van
ECTS credits: 10
Language of instruction: English

Publication dates timetable/results in the Student Portal

Deadline publication timetable
The date on which the timetable of this module is available: 15-12-2023

Deadline publication final result
The date on which the final grade of this module is available: 29-3-2023


Resit booking

Exam booking for a test in current academic year (resit)
You will be booked automatically for the resit in one of our resit periods. You may check our calenders to find out which modules can be retaken and when: https://intranet.maastrichtuniversity.nl/nl/fhml-studenten/studieverloop/wanneer-wat
As of one week before the resit test takes place, you can check in Student Portal if you are booked correctly: Student Portal > My Courses > More actions. The test will also be visible in your time table.

Exam booking for a test from a previous academic year (exam only)
All students who have not passed the test for this module in a previous academic year, will be booked automatically for the test during the regular block period. You will be enrolled in the new course in Canvas but not scheduled for a tutorial group and other educational activities. If you do not wish to participate in this test at the end of the regular block period please de-register via askFHML.

Resit date: 9-7-2024

Though great care has been taken to assure the accuracy of the information on fhmlweb, the FHML cannot be held responsible for possible printing errors, incomplete information, or misinterpretations. Additionally, the FHML reserves the right to make changes to this information.


Course information

Description: EN:

This is the first course for the Regenerative Medicine (RM) specialization within the Biomedical Sciences (BMS) Master’s program. This first block will provide the student with a solid foundation of knowledge in the interdisciplinary field of RM. At its core, RM aims to replace, engineer, or regenerate tissues and organs in order to establish normal function in the human body. Not falling completely within a traditional discipline, researchers and teams within RM combine fundamental physical and biomedical sciences with technology and engineering in order to discover novel methods of regenerating the body. With successes, scientists within RM must also be able to effectively translate this scientific knowledge into a useful clinical therapy. In this first course, students will learn the basics in not only the biological science of regeneration, including stem cell biology and pathophysiology, but also the technology behind RM, including materials science, chemistry, biofabrication, and computational modeling. This intensive course employs a variety of educational forms in order to both give an overview of the field and allow students to dig into topics of interest. Students will learn to work in teams, to think critically utilizing the scientific method, and to communicate across the borders of traditional disciplines. Already in this first block, the acquired knowledge will directly be applied to propose new solutions for state-of-the-art RM case studies.

Goals: EN:

Understand the molecular processes of wound healing and modulation of tissue homeostasis, and how these mechanisms can be leveraged in the development of regenerative therapies.

 

Obtain working knowledge of both a cell’s (or tissue’s) immediate natural environment, and the current uses of biomaterials to provide artificial environments for tissue growth.

 

Understand the successes and failures of current (stem) cell regenerative approaches.

 

Understand the different applications of organoid technology for studying development, homeostasis, tissue repair, and diseases.

 

Be able to describe the composition and organization of ECM (the original biomaterial) and understand the synthesis, structure, and degradation of therapeutic biomaterials.

 

Be able to describe processing technologies used to fabricate biomaterials into 3D scaffolds for tissue engineering, and be able to identify what the important factors of scaffold design are.

 

Understand the basics of microfabrication techniques and the working concepts of bioreactors and organ-on–a-chip.

 

Understand the importance of the cell-material interface for tissue engineering, and be able to explain how Materiomics approaches can aid in the designing of this interface.

 

Be able to critically assess the quality aspects of a research question, methodology, and results. Be able to make supported decisions when designing a regenerative medicine experiment.

 

Be able to clearly present and discuss scientific research in the field of regenerative medicine to those within and outside of the field.

Key words: EN:
Organ and tissue regeneration Biomaterials Tissue engineering Stem cell therapy Interdisciplinary Regenerative medicine
Literature: This is the link to Keylinks, our online reference list.  
Teaching methods:
  • Assignment(s)
  • Work in workgroup(s)
  • Lecture(s)
  • Paper(s)
  • Problem Based Learning
  • Presentation(s)
  • Training(s)
  • Working visit(s)
Assessments methods:
  • Final paper
  • Participaion
  • Presentation
  • Written exam

This page was last modified on:26-4-2023
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