Faculty of Health, Medicine and Life Sciences

Module Information
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MBS1102  - Clinical and Applied Genetics and Genomics

Period 4: from 11-3-2024 to 10-5-2023
Coordinator: Gerards, M.
ECTS credits: 10
Language of instruction: English

Publication dates timetable/results in the Student Portal

Deadline publication timetable
The date on which the timetable of this module is available: not applicable

Deadline publication final result
The date on which the final grade of this module is available: 3-6-2023

Resit booking

Exam booking for a test in current academic year (resit)
You will be booked automatically for the resit in one of our resit periods. You may check our calenders to find out which modules can be retaken and when: https://intranet.maastrichtuniversity.nl/nl/fhml-studenten/studieverloop/wanneer-wat
As of one week before the resit test takes place, you can check in Student Portal if you are booked correctly: Student Portal > My Courses > More actions. The test will also be visible in your time table.

Exam booking for a test from a previous academic year (exam only)
All students who have not passed the test for this module in a previous academic year, will be booked automatically for the test during the regular block period. You will be enrolled in the new course in Canvas but not scheduled for a tutorial group and other educational activities. If you do not wish to participate in this test at the end of the regular block period please de-register via askFHML.

Resit date: 12-7-2024

Though great care has been taken to assure the accuracy of the information on fhmlweb, the FHML cannot be held responsible for possible printing errors, incomplete information, or misinterpretations. Additionally, the FHML reserves the right to make changes to this information.

Course information

Description: EN:

In conjunction with course 1101 ‘Advanced Principles of genetics and genomics’, course 1102 (Clinical and applied genetics and genomics) makes up the specialization track ‘Genetics and Genomics’. This course aims at providing the students with a broad knowledge and expertise in the field of genetics and genomics, and more specifically how these technologies can be applied to scientific research questions, the diagnosis of human diseases in the clinic, and forensics.

This course will elaborate further on genetic fundamentals discussed in the previous courses (1001 and 1101) and includes amongst others currently applied analyses in the clinic as well as some unusual genetic phenomena. Furthermore, state‐of‐the‐art technologies applied in genetic and genomic studies will be discussed including their applications in clinical practice, which, as students will learn, is not as straightforward as seen in certain popular media (eg. CSI, Flikken Maastricht and other TV‐series). Moreover, researchers in the fields of genetics and genomics are confronted with numerous ethical issues restraining their studies. The students will be introduced to some of these ethical problems and challenged how to handle these in practice.

models, cellular models and animal models).in silico An interesting additional skill the student will learn is to implement acquired knowledge from the courses (1001, 1101 and 1102) in the study of different model systems in genetic research (

Based on this knowledge as well as the input of expert staff lectures, the students will get the chance to work in groups on a scientific project application. This will make them aware of the complexities involved in the project writing process, but also will prepare them for a future role in the scientific community.
Goals: EN:
      • ILO1102.1 Explain genetic and genomic technology used in precision medicine and diagnostics of genetic disorders.

      • ILO1102.2 Know the main genomic mechanisms and involved signalling pathways underlying cancer development, cardiovascular and neurological diseases.

      • ILO1102.3 Explain advantages/disadvantages when utilizing genetic testing in research and clinical applications.

      • ILO1102.4 Know which tools are available to model genetic disorders, and apply them to modelling genetic disorders for research and clinical applications.

      • ILO1102.5 Apply the concepts of molecular genetics to design novel research projects in genetics and precision medicine.

Overall Goal: At the end of this course, each student has gained a high level of knowledge on the use of genetic and genomic techniques in research and clinical diagnostics.

Key words: EN:
advanced genetics genomics epigenetics clinical diagnostics research applications gene expression data analysis ethical societal issues forensics
Literature: This is the link to Keylinks, our online reference list.  
Teaching methods:
  • Assignment(s)
  • Work in workgroup(s)
  • Lecture(s)
  • Paper(s)
  • Problem Based Learning
  • Presentation(s)
  • Skills
  • Training(s)
  • Working visit(s)
Assessments methods:
  • Assignment
  • Attendance
  • Final paper
  • Participaion
  • Presentation
  • Written exam

This page was last modified on:9-4-2020
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