Faculty of Health, Medicine and Life Sciences

Module Information
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BGZ2026  - The Basic Principles of Pharmacology

Period 6: from 10-6-2024 to 5-7-2024
Coordinator: Hartog, G. den
ECTS credits: 5
Language of instruction: English

Publication dates timetable/results in the Student Portal

Deadline publication timetable
The date on which the timetable of this module is available: 17-5-2024

Deadline publication final result
The date on which the final grade of this module is available: 9-7-2024

Resit booking

Exam booking for a test in current academic year (resit)
You will be booked automatically for the resit in one of our resit periods. You may check our calenders to find out which modules can be retaken and when: https://intranet.maastrichtuniversity.nl/nl/fhml-studenten/studieverloop/wanneer-wat
As of one week before the resit test takes place, you can check in Student Portal if you are booked correctly: Student Portal > My Courses > More actions. The test will also be visible in your time table.

Exam booking for a test from a previous academic year (exam only)
All students who have not passed the test for this module in a previous academic year, will be booked automatically for the test during the regular block period. You will be enrolled in the new course in Canvas but not scheduled for a tutorial group and other educational activities. If you do not wish to participate in this test at the end of the regular block period please de-register via askFHML.

Resit date: 18-7-2024

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Course information

Description: NL:


The module’s subjects will be provided in an integrative setting of PBL cases, lectures and practical trainings. The PBL cases will be ammended by lectures which also hook up with topics of this module and prior modules. The presentation of a real patient case illustrates how pharmacology is implemented in clincal practice. An important part of this module consists of a practical in which students perform a clinical trial on the effects of nutrients on the kinetics of a drug. This practical will be completed by an assignment. The results of all other practicals will be presented and discussed in the tutorial group meetings enabling their seamless embedding in the other block's subjects.   This module provides an introduction into the basic principles of pharmacology and toxicology. Pharmacology and toxicology deal with the effects of biologically active compounds on (patho)physiological processes. The disciplines are subdivided into two general subjects: (1) pharmacodynamics, which assesses the effects of a compound in the human physiology, and (2) pharmacokinetics, which assesses the fate of a compound in the human body. Both subjects determine the therapeutic effectivity and toxicity of a drug in humans and are influenced by genetic factors like polymorphisms in genes of drug metabolizing enzymes and by the concomitant intake of nutrients. Also subjects like drug development (preclinical and clinical phases) and the set-up of a clinical trial protocol for medical-ethical approval are covered.
Goals: NL:


Key competences 

The student is able to...

  1. describe the basic principles of pharmacodynamics, pharmacokinetics and drug development.
  2. explain the effects of nutrients and genetic polymorphisms on the action of drugs.
  3. calculate basic pharmacodynamic and pharmacokinetic parameters and to use them for the prediction of drug action.
  4. discuss the design and execution of clinical trials to investigate the efficacy of drugs.
  5. evaluate clinical trial data and present them to qualified persons so that they can follow and understand the outcomes and conclusions.





Key words: NL:

pharmacokinetics, ADME, pharmacodynamics, receptor, toxicity, polymorphism, clinical study, drugs
Literature: This is the link to Keylinks, our online reference list.  
Teaching methods:
  • Assignment(s)
  • Work in workgroup(s)
  • Lecture(s)
  • Problem Based Learning
  • Research
  • Skills
  • Training(s)
Assessments methods:
  • Assignment
  • Attendance
  • Participaion
  • Written exam

This page was last modified on:24-4-2020
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